The National Indian Health Board (NIHB) created a response plan template as a resource for Tribes, Pueblos, and Nations to use in developing COVID-19 or other outbreak response plans or in cross-walking with existing plans. In recognition of Tribal sovereignty and self-governance, the response template acknowledges that Tribes, Pueblos, and Nations may differ in respect to their approaches to COVID-19-related mitigation and response. Therefore, this document serves as a starting or reference point for Tribal nations to review and determine what content may be relevant to their unique circumstances.